M110 was serendipitously discovered on August 10, 1773 by w:Charles Messier, who was making observations of the Andromeda Galaxy at the time. The galaxy was independently discovered by w:Caroline Herschel on August 27, 1783; her brother w:William Herschel described her discovery in 1785. Although the galaxy was not originally included in Messier's first catalogue, it was later added by w:Kenneth Glyn Jones in 1966. M110 remains the last object added to the Messier catalog.
In 1999, Johnson and Modjaz discovered a w:nova in M110.
↑R. W. Sinnott, editor (1988). The Complete New General Catalogue and Index Catalogue of Nebulae and Star Clusters by J. L. E. Dreyer. Sky Publishing Corporation and Cambridge University Press. ISBN0-933-34651-4.