Radiation Oncology/NHL/Cutaneous
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Cutaneous Lymphoma
- WHO; 2008 PMID 15692063 -- "WHO-EORTC classification for cutaneous lymphomas." (Willemze R, Blood. 2005 May 15;105(10):3768-85.)
- Classification system for primary cutaneous lymphomas
| Histology | Frequency | 5-year DSS | Clinical Course |
|---|---|---|---|
| T-cell cutaneous lymphomas | |||
| Mycosis fungoides | 44% | 88% | Indolent |
| Variants of MF | <5% | 80-100% | Indolent |
| Sezary syndrome | 3% | 24% | Aggressive |
| Primary cutaneous anaplastic large cell lymphoma (CD30+) | 8% | 95% | Indolent |
| Lymphomatoid papulosis (CD30+) | 12% | 100% | Indolent |
| Subcutaneous panniculitis-like T-cell lymphoma | 1% | 82% | Indolent |
| Extranodal NK/T-cell lymphoma, nasal type | <1% | -- | Aggressive |
| Primary cutaneous T-cell lymphoma, unspecified | 2% | 16% | Aggressive |
| B-cell cutaneous lymphomas | |||
| Primary cutaneous marginal zone B-cell lymphoma | 7% | 99% | Indolent |
| Primary cutaneous follicle center lymphoma | 11% | 95% | Indolent |
| Primary cutaneous diffuse large B-cell lymphoma, leg type | 4% | 55% | Intermediate |
| Primary cutaneous diffuse large B-cell lymphoma, other | <1% | 50% | Intermediate |