Radiation Oncology/Toxicity/Thyroid
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Hypothyroidism
- Cleveland Clinic; 2001 PMID 11753963 -- "Hypothyroidism: a frequent event after radiotherapy and after radiotherapy with chemotherapy for patients with head and neck carcinoma." (Mercado G, Cancer. 2001 Dec 1;92(11):2892-7.)
- Retrospective. 143 patients, H&N cancer, RT or chemo-RT. TSH measured regularly. Median F/U 4.4 years
- Outcome: 5-year hypothyroidism 48%, 8-year 67%. Median time-to-development 1.4 years
- Conclusion: Incidence of hypothyroidism higher than generally reported