Orthopaedic Surgery/Infections

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Orthopaedic Surgery

INTRODUCTION · AUTHORS · ACKNOWLEDGEMENTS · NOTE TO AUTHORS
1.Basic Sciences · 2.Upper Limb · 3.Foot and Ankle · 4.Spine · 5.Hand and Microsurgery · 6.Paediatric Orthopaedics · 7.Adult Reconstruction · 8.Sports Medicine · 9.Musculoskeletal Tumours · 10.Injury · 11.Surgical Procedures · 12.Rehabilitation · 13.Practice
Current Chapter: Basic Sciences


Infections
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By present account 1,407 pathogens can infect humans; pathogens defined here include viruses, bacteria, parasites protazoa and fungi. Infection results in contact between human cells and a pathogen. Chemical interactiion occurs between the two and from the standpoint of the human cell can be categorized as non-self recognition, and defense. This local encounter then gives rise to a systemic response to the infection which attempts to favor containment, eradication and elimination of the invader, or it may reflect the toxic effect of the pathogen on the organism as a whole. In some cases the immune response to infection results in late sequelae leading it seems to the development of auto-immune based diseases.