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Radiation Oncology/Oncovirus

From Wikibooks, open books for an open world
  • An oncovirus is a virus that can cause cancer
  • This term originated from studies of acutely transforming retroviruses in the 1950–60s, when the term "oncornaviruses" was used to denote their RNA virus origin
  • With the letters "RNA" removed, it now refers to any virus with a DNA or RNA genome causing cancer and is synonymous with "tumor virus" or "cancer virus"
  • The vast majority of human and animal viruses do not cause cancer, probably because of longstanding co-evolution between the virus and its host
  • Oncoviruses have been important not only in epidemiology, but also in investigations of cell cycle control mechanisms such as the retinoblastoma protein

Human Papillomavirus (HPV)

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Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV)

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Epstein-Barr Virus (EBV)

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Human T-Cell Leukemia Virus (HTLV-1)

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Kaposi's Sarcoma-Associated Herpesvirus (KSHV)

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