Radiation Oncology/Breast/Guidelines

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Front Page: Radiation Oncology | RTOG Trials

Breast: Main Page | Staging | Breast Overview | Prevention | Benign | DCIS | LCIS | Paget's | Phyllodes tumor | Early stage | Advanced stage | Post mastectomy | Inflammatory | Partial breast irradiation | Regional lymphatics | Hormonal therapy | Chemotherapy | RT technique | Recurrence | Toxicity of RT | Randomized | NSABP trials

Breast Cancer Official Guidelines

Screening topics[edit]


Testing / Workup topics[edit]

Tumor Markers

  • ASCO: Tumor markers in breast cancer
    • 2007 Guideline link PMID 17954709 -- "American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer." (Harris L, J Clin Oncol. 2007 Nov 20;25(33):5287-312.)

HER2 testing

  • ASCO:
    • 2013 Guideline link PMID 24101045 -- "Recommendations for Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Update" (Wolff AC, J Clin Oncol. 2013 Oct 7 [Epub ahead of print])

Clinical / treatment topics[edit]


Sentinel Lymph Node

  • ASCO:
    • 2014 PMID 24663048 -- "Sentinel Lymph Node Biopsy for Patients With Early-Stage Breast Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update" (Lyman GH, J Clin Oncol. 2014 Mar 24. [Epub ahead of print])

Breast Conservation Therapy

  • SSO / ASTRO: Margin width
    • 2014 -- "Society of Surgical Oncology–American Society for Radiation Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Stages I and II Invasive Breast Cancer"
      • PMID 24516019 Abstract (Moran MS, J Clin Oncol. 2014 Feb 10. [Epub ahead of print])
      • PMID 24521674 (Moran MS, Int J Radiat Oncol Biol Phys. 2014 Mar 1;88(3):553-64.)
      • PMID 24711553 (Buchholz TA, J Clin Oncol. 2014 Apr 7. [Epub ahead of print]) - ASCO endorsement of SSO/ASTRO guideline.
  • ASTRO: Whole Breast Fractionation
    • 2010 PMID 20638191 -- "Fractionation for Whole Breast Irradiation: An American Society for Radiation Oncology (ASTRO) Evidence-Based Guideline." (Smith BD, Int J Radiat Oncol Biol Phys. 2010 Jul 15. [Epub ahead of print])
  • DEGRO: Breast Conserving Therapy
    • 2007 PMID 18040609 -- "DEGRO practical guidelines for radiotherapy of breast cancer I: breast-conserving therapy." (Sautter-Bihl ML, Strahlenther Onkol. 2007 Dec;183(12):661-6.)
  • ACR: Appropriateness Criteria

Accelerated Partial Breast Irradiation

  • GEC-ESTRO: APBI Recommendations
    • 2010 PMID 20181402 -- "Patient selection for accelerated partial-breast irradiation (APBI) after breast-conserving surgery: Recommendations of the Groupe Européen de Curiethérapie-European Society for Therapeutic Radiology and Oncology (GEC-ESTRO) breast cancer working group based on clinical evidence (2009)." (Polgar C, Radiother Oncol. 2010 Mar;94(3):264-273. Epub 2010 Feb 22.)
  • ASTRO: APBI Consensus Statement
    • 2009 PMID 19545784 -- "Accelerated partial breast irradiation consensus statement from the American Society for Radiation Oncology (ASTRO)." (Smith BD, Int J Radiat Oncol Biol Phys. 2009 Jul 15;74(4):987-1001.)
  • ABS: APBI Guideline
  • ASBS: APBI Consensus Statement

Postmastectomy Radiation

  • DEGRO: Postmastectomy RT, regional lymphatics, and locally advanced disease
    • 2008 PMID 19016032 -- "DEGRO practical guidelines for radiotherapy of breast cancer II. Postmastectomy radiotherapy, irradiation of regional lymphatics, and treatment of locally advanced disease." (Sautter-Bihl ML, Strahlenther Onkol. 2008 Jul;184(7):347-53.)
  • ASCO: Clinical Practice Guideline
    • 2001 PMID 11230499 -- "Postmastectomy radiotherapy: clinical practice guidelines of the American Society of Clinical Oncology." (Recht A, J Clin Oncol. 2001 Mar 1;19(5):1539-69.)
  • ASTRO: PMRT Consensus Statement
    • 1999 PMID 10421530 -- "Consensus Statement on postmastectomy radiation therapy." (Harris JR, Int J Radiat Oncol Biol Phys. 1999 Jul 15;44(5):989-90.)

Locally Advanced Breast Cancer


RT in Metastatic Disease

  • DEGRO: Brain Metastases and Leptomeningeal Carcinomatosis
    • 2010 PMID 20127222 -- "DEGRO Practical Guidelines for Palliative Radiotherapy of Breast Cancer Patients: Brain Metastases and Leptomeningeal Carcinomatosis." (Feyer P, Strahlenther Onkol. 2010 Feb;186(2):63-69. Epub 2010 Jan 26.)
  • DEGRO: Bone Metastases and Spinal Cord Compression
    • 2009 PMID 19714302 -- "DEGRO practice guidelines for palliative radiotherapy of metastatic breast cancer: bone metastases and metastatic spinal cord compression (MSCC)." (Souchon R, Strahlenther Onkol. 2009 Jul;185(7):417-24. Epub 2009 Aug 28.)

Curative Approach to Metastatic Disease

  • ESO-MBC: Can metastatic breast cancer be cured?
    • 2010 PMID 20220104 -- "International guidelines for management of metastatic breast cancer: can metastatic breast cancer be cured?" (Pagani O, J Natl Cancer Inst. 2010 Apr 7;102(7):456-63. Epub 2010 Mar 10.)

Follow-up topics[edit]


  • ASCO: Breast Cancer Follow-Up and Management After Primary Treatment
    • 2012 Guideline link PMID 23129741 -- "Breast Cancer Follow-Up and Management After Primary Treatment: American Society of Clinical Oncology Clinical Practice Guideline Update" (Khatcheressian JL, J Clin Oncol. 2013 Jan 14. -- early release)