We usually write DA for the dopamine neurotransmitter and 5-HT for the serotonin neurotransmitter. These two neurotransmitters are usually slow and a lot less common than the major ones. They originate in brainstem, but they are released throughout the entire brain and spine.
In this section we will attempt to answer what depression is; what anxiety is; how we treat them; and what antidepressants are.
Antidepressants[edit | edit source]
- Selective serotonin reuptake inhibitor (SSRI)
- This inhibits the 5-HT reuptake.
- Tricyclic antidepressant (TCA)
- This inhibits 5-HT and NE reuptake, and antagonizes ACh receptors.
- Monoamine oxidase inhibitor (MAOI)
- This inhibits MAO breakdown of 5-HT, NE, and DA.
- Serotonin-norepinephrine reuptake inhibitor (SNRI)
- This inhibits 5-HT and NE reuptake.
Examples[edit | edit source]
- Mirtazapine: Antagonizes presynaptic NE receptors and thus boosts the release of NE and 5-HT receptors, and antognises specific postsynaptic 5-HT receptors to relieve anxiety. 
- Bupropion: Inhibits NE and DA reuptake. Making it very good for stimulant addicts.
- Atomoxetine: Inhibits NE reuptake. Making it very good for Attention Deficit Hyperactivity Disorder (ADHD).
References[edit | edit source]