Obstetrics and Gynecology/Diabetes in the Pregnant Female

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Epidemiology[edit | edit source]

Etiology[edit | edit source]

Pathophysiology[edit | edit source]

  • Factors released from the placenta (i.e. human placental lactogen, growth hormone, progesterone, and glucocorticoids) may aggravate maternal insulin resistance.
  • Increased insulin requirements during pregnancy may reveal a maternal incapacity to produce insulin from her pancreatic beta-cells.
  • Preexisting diabetes in the mother may worsen any already-present complications of diabetes.

Clinical Presentation[edit | edit source]