ID Board Review/Bacterial Diseases/Gram-negative Rods (GNR)/Enterobacteriaceae/Shigella
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Histology[edit | edit source]
- Gram-negative bacilli in Enterobacteriaceae
- Nonmotile, nonencapsulated
- Doesn't ferment lactulose and lacks urease activity
Pathophysiology[edit | edit source]
- Low infectious inoculum
- One of the most communicable forms of bacterial diarrhea w 80% of infections transmitted from person to person
Clinical Presentations[edit | edit source]
- Often in young/pediatric patients
- Asymptomatic to severe dysentery
- Often watery diarrhea, but bloody diarrhea is often
- Can progress to HUS
Endemic Areas/Environments[edit | edit source]
- Daycares, often daycare attendance
- International travel
- STI among MSM
- Concomitant HIV infection might modulate transmission