Introdcution to Genetics
One goal of genetic research is to identify genes that contribute to complex diseases, and understand how these genes are influenced by a person's environment and lifestyle choices.
This module collects the information of hereditary risks, family history and genetic disorders. GNU Health includes the NCBI and Genecards information, more than 4.200 genes associated to diseases.
The National Center for Biotechnology Information (NCBI) is part of the United States National Library of Medicine (NLM), a branch of the National Institutes of Health. The NCBI advances science and health by providing acces to biomedical and genomic information.
Genecards is a database of human genes that provides genomic, proteomic, transcriptomic, genetic and functional information on all known and predicted human gene.
As we can see in the next example, the patient Ana Betz has BRCA1 disease gene. GNU Health includes the specific information of the gene including official symbol, official long name, affected chromosome, dominance and location.
Family history and some inherited genetic mutations affect breast cancer risk in both men and women. Having an immediate family member with a history of breast cancer increases your own risk of breast cancer. Although rare, mutations in the BRCA1 and BRCA2 genes increase risk of breast and other cancers.
GNU Health helps you searching the disease gene through a very useful searching filter with different categories such as affected chromosome, dominance, official long name and official symbol.
In addition to genetic risks, GNU Health also includes patient genetic family diseases. As we can see in the next example, the patient has a relative with Marfan's syndrome, specifically the maternal grandfather.
Gathering a complete and accurate family medical history is becoming more important as genetic medicine explains more diseases. As genes are passed down from generation to generation, medical conditions and diseases, or the increased risk for disease, tend to run in families due to gene abnormalities. Health care professionals now better understand how irregular genes are passed from one generation to the next and have an increased ability to test for hundreds of inherited illnesses.
GNU Health shows extra info related to diseases including the name, code and main disease category, genetic data and a free text box for adding relevant extra info.