Diagnostic Radiology/Musculoskeletal Imaging/Tumors Basic/Telangiectatic Osteosarcoma

Telangiectatic osteosarcoma This is a rare variant that present as an entirely lytic bone lesion with a much less aggressive appearance. Typical age is 10–25 years of age and lesions commonly occur in the metadiaphysis of long bones, similar to conventional osteosarcoma. Lesions are more geographic but portions of the mass can have a wide zone of transition and cortical breakthrough with a soft tissue mass. Lesions are highly vascular, partly necrotic and often have large pools of blood within them with soft tissue peripherally and along septa. Leading to an MRI appearance with internal septa, fluid fluid levels, peripheral heterogeneity. Telangiectatic osteosarcoma commonly enhances. Differential includes aneurysmal bone cyst and giant cell tumor.

References

• Osteosarcoma by Todd Kooy, M.D., University of Washington Department of Radiology
• Treatment of Osteosarcoma (cancer.gov)
• Wikipedia Listing for Osteosarcoma
• Murphey MD, Robbin MR, MacRae GA, Flemming DJ, Temple HT, Kransdorf MJ. The many faces of osteosarcoma. RadioGraphics 1997;17(5).
• Osteosarcoma (Emedicine)