Chemical Sciences: A Manual for CSIR-UGC National Eligibility Test for Lectureship and JRF/Fluorine-19 NMR

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Fluorine-19 NMR (for nuclear magnetic resonance) is an analytical technique. 19F has a spin of 1/2, and a relative abundance of 100 %, making measurements very fast (comparable with 1H NMR). Integrals are reliable due to the lack of a nuclear Overhauser effect (fluorine forms one bond only). Fluorine-containing compounds are occasionally encountered in organic chemistry (fluorinated compounds are popular in pharmaceutical applications), and in inorganic chemistry (e.g. the trifluoroacetate anion or counter-ligand).

The reference compound for 19F is CFCl3.[1]