Chemical Sciences: A Manual for CSIR-UGC National Eligibility Test for Lectureship and JRF/Advanced Microscopy Group

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Advanced Microscopy Group or AMG is a manufacturer of microscopes based in Mill Creek, Washington.[1] Their products include the EVOS Microscope, a digital inverted microscope for use in fluorescence and transmitted light applications.[2] It utilizes a Light-emitting diode illumination system. The integrated microprocessor and imaging system, and a high resolution digital camera let users process and analyze live and captured images. The 15-inch Liquid crystal display replaces the traditional eye pieces. Software features include time-lapse, cell counting and transfection analysis.

A key feature of the EVOS fluorescence microscope is its LED-based light cube system. Each light cube integrates the illumination source, the light engine and the fluorescence filters into a single unit, removing need for alignment or calibration. The optical path is shortened and the light cube delivers bright illumination intensities. Each LED lasts for more than 50,000 hours. LEDs can be adjusted and controlled, and the chance of photobleaching or phototoxicity is reduced.

The embedded microprocessor gives users control of image acquisition and management. Mouse-controlled user interface allows adjusting illumination levels, balancing fluorescence and transmitted light channels, and capturing image data and saving it to a portable USB flash drive.

This portable unit can be placed in a cell culture hood for sensitive cell isolation procedures and is equipped with a DVI output that can be connected to an external display or monitor.