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English: The mouse and human visual systems share basic similarities but differ in complexity. Right, a schematic of the rodent visual system. The eyes in the rodent are positioned laterally resulting in hemi-panoramic vision that includes a narrow central binocular zone (purple) flanked by regions of monocular vison (blue and red). Retinal ganglion cells (RGCs) with receptive fields in the binocular zone from the ipsilateral eye (blue) send a minor projection to a discrete patch in the lateral geniculate nucleus (LGN), whereas the contralateral eye (red) provides the predominant innervation to the LGN. Thalamocortical projections from these two regions converge on the binocular zone (purple) in primary visual cortex (V1). Left, a schematic of the human visual system. Forward facing eyes provide for a more expansive zone of binocular vision. Retinal ganglion cells from the two eyes send similar projections to the LGN that are distributed to eye-specific laminae. Thalamocortical projections similarly converge on V1 (purple) but also maintain evident regions of enrichment termed ocular dominance columns.
Date Published online: 02 October 2014
Source Priebe NJ and McGee AW (2014) Mouse vision as a gateway for understanding how experience shapes neural circuits. Front. Neural Circuits 8:123. doi: 10.3389/fncir.2014.00123
Author Priebe NJ and McGee AW

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