USMLE Step 1 Review/Pathology

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5 SIGNS OF INFLAMMATION (as described by Celsus)[edit]

  • Redness/Erythema (Rubor)
  • Raised temperature (Calor)
  • Swelling (Tumor)
  • Pain (Dolor)
  • Loss of Function (Functio Laesa)

HYPERSENSITIVITY REACTIONS[edit]

Goombs classification: "Anna Cycled Immediately Downhill--Gell & Goombs" or "ACID".

  • Type I Anaphylaxis
  • Type II Cytotoxic-mediated
  • Type III Immune-complex
  • Type IV Delayed hypersensitivity