Radiation Oncology/Prostate/Cryotherapy

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Front Page: Radiation Oncology | RTOG Trials | Randomized Trials

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Prostate: Main Page | Prostate Overview | Screening and Prevention | Workup | Natural History | External Beam RT | IMRT | Androgen Suppression Therapy | Brachytherapy | Protons | Prostatectomy | Adjuvant RT after Prostatectomy | Salvage RT | Chemotherapy | Localized prostate cancer | Node Positive | Advanced disease | Recurrence after RT | Cryotherapy | RTOG Prostate Trials | Randomized Evidence

Cryotherapy (Cryosurgery)

[edit] Cryotherapy for salvage after RT

[edit] Salvage RT after cryotherapy

  • Allegheny General (Pittsburgh) (1990-99)
    • 49 pts treated for isolated local recurrence after cryotherapy (rising PSA or positive biopsy; negative metastatic workup). 88% had high risk disease initially (PSA>10,G>=7,or >=T2b).
    • RT was 3D-CRT in 45 of 49 pts, 64.8 Gy to the P+SV.
    • PMID 11068312, 2000 — "Salvage radiotherapy for prostate cancer recurrence after cryosurgical ablation." Burton S et al. Urology. 2000 Nov 1;56(5):833-8.
      • Median f/u 32 m. Biochemical control in 61%; associated with higher RT dose, lower pre-RT PSA.
      • No grade 3-4 acute GI or GU toxicity. 1 pt with urethral stricture. No pts with urinary incontinence.
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