Radiation Oncology/Bone/Background

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Epidemiology[edit]

Incidence: 8 per 1,000,000.
2440 cases in 2004.

Incidence: osteosarcoma (35%), chondrosarcoma (30%), Ewing's sarcoma (16%)


Histology[edit]

Histologic Origin Proportion Malignant Tumor
Hematopoietic 41% Myeloma
Chondrogenic 21% Chondrosarcoma
Osteogenic 19% Osteosarcoma
Unknown/bone marrow 10% Ewing's tumor

Malignant giant cell tumor
Adamantinoma

Fibrogenic 4% Fibrosarcoma
Notochordal 3% Chordoma
Vascular 2% Hemangioendothelioma

Hemangiopericytoma

Note: Adapted from Dahlin DC, Bone tumors: general aspects and data on 6,221 cases, 3rd ed. 1978

Location[edit]

  • EG-MODE
    • Epiphysis: Giant cell
    • Metaphysis: Osteosarcoma
    • Diaphysis: Ewing's sarcoma