Radiation Oncology/Cancer Syndromes/Cockayne Syndrome
Jump to navigation
Jump to search
|
Cockayne Syndrome
- Mutations in ERCC6 and ERCC8, part of the NER pathway for single strand DNA damage repair
- Autosomal recessive syndrome
- Growth failure, impaired development of CNS, photosensitivity, premature aging
- No cancer predisposition