GENtle/Release notes

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The GENtle manual

About - FAQ - Setup - DNA - Protein - PCR and Primer Design - Sequencing - Alignments - Calculators - Virtual Gel - Image Viewer - Tools and Dialogs - Web interface - Graphs and plots - DNA map - Sequence map - Dot plot - Restriction Identifier

1.9.5 alpha 2 (in preparation)[edit | edit source]

  • Source code reorganisation to prepare for automated testing.
  • Documentation transitioned from Wikibooks to Markdown into the code tree (docs/manual.adoc).
  • https access to NCBI web services like pubmed

This version is yet not stable enough for professional work.

1.9.5 alpha 1[edit | edit source]

Initial port to wxWidgets 3.

1.9.4[edit | edit source]

Last version available for wxWidgets 2

1.9.0[edit | edit source]

Additions

  • Chinese language interface

1.8.8[edit | edit source]

Additions

  • DNA can optionally be displayed in lowercase
  • In the PCR module, amino acids that change due to primers are now marked in the resulting amino acid sequence

Bugfixes

  • Silent mutation now shows correct fragment lengths
  • Fixed screen update after undo bug
  • Fixed dialog layout on OSX

1.8.6[edit | edit source]

Additions

  • Sequencer data can not be viewed "in part" (via both context menu and command line options)
  • Amino acid structures can now be displayed inline in the amino acid module
  • The font size of the sequence can now be adjusted (for both screen and printer)

Bugfixes

  • Find dialog now marks found restriction enzymes with correct length

1.8.5[edit | edit source]

Additions

  • ~200 new restriction enzymes
  • restriction enzyme can now be updated from ReBase
  • partial restrictions can now be added to virtual gels
  • virtual gels can now be copied/saved as images
  • Lane names can now be changed in virtual gels

Bugfixes

  • Fixed bug for non-palindromic restriction enzymes
  • Fixed bug preventing saving of some plasmid maps

1.8.4[edit | edit source]

Additions

  • Clone Manager import (limited due to lack of format description)

Bugfixes

  • Fixed bug in auto-annotation

1.8.3[edit | edit source]

Additions

  • Can now chose to search for sequence, items, enzymes, translations in Find Dialog
  • Can now edit and delete restriction enzymes

Bugfixes

  • Minor calculator bugs fixed
  • Inserting restriction enzyme sites in PCR while editing used to crash, now fixed

1.8.2[edit | edit source]

Additions

  • Option for using two toolbars
  • Larger toolbar icons for Mac
  • Highlighting function in Find dialog
  • Online tools (via context menu) for DNA, protein, and alignments
  • Module/Dialog-sensitive online help

Bugfixes

  • fixed module refresh bug
  • fixed search for restriction enzymes in Find dialog
  • fixed coding region detection bug under Mac
  • fixed virtual gel printing bug

1.8.1[edit | edit source]

Notes

  • TIFF export deactivated due to patent enforcement

Additions

  • Alignments can now be edited markup-wise
  • Startup tips (re-)enabled

Bugfixes

  • New sequences with more than 64KB text can now be entered again
  • "OK" in Silmut/WhatCutsHere dialog with no entry selected doesn't crash anymore
  • DNA markers can now be added and edited via "marker.txt"
  • siRNA duplexes fix for features that cross the "zero" point
  • fixed protease display in DNA module
  • fixed 3'->5' strand extraction
  • fixed enumeration bug when adding databases
  • fixed restriction enzyme recognition/display bug

1.8.0[edit | edit source]

Additions

  • new icons for Windows
  • multiple DNA markers for virtual gel
  • find siRNA duplexes
  • turn plasmid map
  • enforcing global (alternative) translation table

Bugfixes

  • better Mac/Linux integration
  • Miscellaneous
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