Chess Opening Theory/1. e4/1...a6/2. c4
|St. George Defence|
St. George Defence 
2. c4 
At first sight, it looks like a refutation of St Georges Defence. But Black keeps the powerful ability to play 2...e5, transposing into an open game where White have a misplaced pawn on c4.
2...b5 looks compromised as Black will lose one of the main benefit of the St Georges : the power at the queen side.
Theory table 
'1.e4 a6 2.c4'
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- Batsford Chess Openings 2 (1989, 1994). Garry Kasparov, Raymond Keene. ISBN 0-8050-3409-9.