Chemical Sciences: A Manual for CSIR-UGC National Eligibility Test for Lectureship and JRF/Probe electrospray ionization

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Probe electrospray ionization (PESI) is a modified version of conventional electrospray ionization (ESI), where the capillary for sample solution transferring is replaced by a solid needle with a sharp tip. PESI was first introduced by Kenzo Hiraoka et al. in 2007[1]. Compared with conventional electrospray ionization, high salt tolerance and direct sampling and low sample consumption can be found with PESI. Of course, PESI is not a continuous process at all. Normally, the needle for sampling and spraying can be driven up and down under a frequency of 3-5 Hz.

References[edit | edit source]

  1. ↑ Hiraoka K.; Nishidate K.; Mori K.; Asakawa D.; Suzuki S. (2007). "Development of probe electrospray using a solid needle". Rapid Communications in Mass Spectrometry. 21: 3139–3144. doi:10.1002/rcm.3201.{{cite journal}}: CS1 maint: multiple names: authors list (link)
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