AppleScript Programming/Mail alert
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Note: the following will bring your volume low after raising it with the alert.
From anyone (at "Tools->Rules", create a new rule, add criterion such as "Is not junk email", and for an action, choose "Run AppleScript", selecting the script file for the script below):
tell application "Microsoft Entourage" set volume 10 say "You've got mail!" set volume 1 end tell
From a specific person (at "Tools->Rules", create a new rule, add criterion such as "From"+"Contains"->bob@yahoo.com, and for an action, choose "Run AppleScript", selecting the script file for the script below):
tell application "Microsoft Entourage" set volume 10 say "You've got mail from Bob!" set volume 1 end tell